Semaphorin 5B (SEMA5B)
[Edit]SEMAG; SemG; Sema Domain,Immunoglobulin Domain(Ig),Transmembrane Domain(TM)and Short Cytoplasmic Domain 5B
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Members of the semaphorin protein family, such as SEMA5B, are involved in axonal guidance during neural development. The deduced 1,093-amino acid protein contains an N-terminal signal sequence, followed by a semaphorin domain, 7 thrombospondin type-1 repeats, a putative transmembrane domain, and a short cytoplasmic tail. It also has 13 conserved cysteines and a conserved N-glycosylation site. Northern blot analysis of whole mouse embryos detected Semg at embryonic day 10, and its expression decreased toward birth. During development, Semg was expressed exclusively in the neuroepithelium along the entire anterioposterior axis. In adult animals, Semg was detected only in brain.The deduced 1,202-amino acid protein shares 93% identity with mouse Semg.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPL926Mu01 | Recombinant Semaphorin 5B (SEMA5B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAL926Mu01 | Polyclonal Antibody to Semaphorin 5B (SEMA5B) | WB; IHC; ICC; IP. |
| LAL926Mu71 | Biotin-Linked Polyclonal Antibody to Semaphorin 5B (SEMA5B) | WB; IHC; ICC. | |
| Assay Kits | n/a | CLIA Kit for Semaphorin 5B (SEMA5B) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Semaphorin 5B (SEMA5B) | ELISA Kit Customized Service Offer |
- "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]