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Progestin And AdipoQ Receptor Family, Member III (PAQR3)

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LMPB1; MPRB; RKTG; Raf kinase trapping to Golgi; Progestin and adipoQ receptor family member III

Progestin And AdipoQ Receptor Family, Member III (PAQR3)
CCC L938
HGNC 30130
MGI 2679683
RGD 1310426
UniProt Q6TCH7
The PAQR family of proteins comprises an intriguing group of newly discovered receptors. Although the agonist is known for 5 of the 11 human PAQRs, most are considered “orphan” receptors. The proteinaceous hormone adiponectin functions as an agonist of , a previously uncharacterized member of this family. This is not surprising given that PAQR3 is most closely related to PAQR1 (AdipoR1) and PAQR2 (AdipoR2), which also sense adiponectin.
The identification of adiponectin as an agonist for PAQR3 is of considerable clinical relevance because adiponectin suppresses the proliferation of tumor cells and it has been reported that PAQR3 suppresses tumorigenesis. Thus, the interaction between PAQR3 and adiponectin may help explain the antiproliferative properties of adiponectin.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Progestin And AdipoQ Receptor Family, Member III (PAQR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Progestin And AdipoQ Receptor Family, Member III (PAQR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Progestin And AdipoQ Receptor Family, Member III (PAQR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Progestin And AdipoQ Receptor Family, Member III (PAQR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Progestin And AdipoQ Receptor Family, Member III (PAQR3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Progestin And AdipoQ Receptor Family, Member III (PAQR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Progestin And AdipoQ Receptor Family, Member III (PAQR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Progestin And AdipoQ Receptor Family, Member III (PAQR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Progestin And AdipoQ Receptor Family, Member III (PAQR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Progestin And AdipoQ Receptor Family, Member III (PAQR3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Progestin And AdipoQ Receptor Family, Member III (PAQR3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Progestin And AdipoQ Receptor Family, Member III (PAQR3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Progestin And AdipoQ Receptor Family, Member III (PAQR3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Progestin And AdipoQ Receptor Family, Member III (PAQR3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Progestin And AdipoQ Receptor Family, Member III (PAQR3) ELISA Kit Customized Service Offer
  1. "PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif."J. Mol. Evol. 61:372-380(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization of the topology and functional domains of RKTG."Biochem. J. 414:399-406(2008) [PubMed] [Europe PMC] [Abstract]