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NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1)

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ALS2CR1; CALS-7; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein; Putative GTP cyclohydrolase 1 type 2 NIF3L1

NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1)
CCC L952
HGNC 13390
MGI 1929485
PubMed 12522100
RGD 1310329
UniProt Q9GZT8
Wiki NIF3L1
The mouse and human cDNAs encode deduced proteins of 376 and 377 amino acids, respectively, that share 84% sequence identity. Both proteins show strong homology to proteins of lower species, indicating a high degree of conservation from bacteria to mammals.
Northern blot analysis showed ubiquitous expression of mouse Nif3l1, with a major transcript size of 1.85 kb. RT-PCR analysis demonstrated ubiquitous expression of Nif3l1 throughout mouse embryonic development. Expression analysis on cell lines revealed strong overexpression in a spermatogonia-derived cell line and a teratocarcinoma cell line. A human NIF3L1/GFP fusion protein showed localization of the protein in the cytoplasm.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) CLIA Kit Customized Service Offer
n/a ELISA Kit for NGG1 Interacting Factor 3 Like Protein 1 (NIF3L1) ELISA Kit Customized Service Offer
  1. "Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals."Cytogenet. Cell Genet. 90:330-336(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of three novel genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the juvenile amyotrophic lateral sclerosis (ALS2) critical region at chromosome 2q33-q34: candidate genes for ALS2."Genomics 71:200-213(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification and characterization of NIF3L1 BP1, a novel cytoplasmic interaction partner of the NIF3L1 protein."Biochem. Biophys. Res. Commun. 309:440-448(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]