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Partitioning Defective 3 Homolog (PARD3)

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ASIP; PAR3; Baz; Bazooka; PAR3alpha; PARD3A; SE2-5L16; SE2-5LT1; SE2-5T2; Atypical PKC Isotype-Specific Interacting Protein; CTCL tumor antigen se2-5

Partitioning Defective 3 Homolog (PARD3)
CCC L985
HGNC 16051
MGI 2135608
PubMed 17989107
RGD 620374
UniProt Q8TEW0
Wiki PARD3
PARD3 and PARD6, in turn, formed a quaternary complex with protein kinase C-zeta (PRKCZ) and CDC42. Fluorescence microscopy demonstrated that PARD3 colocalizes with the tight junction protein ZO1 (TJP1), and this colocalization could be disrupted by the expression of the PARD3-binding region of PARD6. PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Partitioning Defective 3 Homolog (PARD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Partitioning Defective 3 Homolog (PARD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Partitioning Defective 3 Homolog (PARD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Partitioning Defective 3 Homolog (PARD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Partitioning Defective 3 Homolog (PARD3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Partitioning Defective 3 Homolog (PARD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Partitioning Defective 3 Homolog (PARD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Partitioning Defective 3 Homolog (PARD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Partitioning Defective 3 Homolog (PARD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Partitioning Defective 3 Homolog (PARD3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Partitioning Defective 3 Homolog (PARD3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Partitioning Defective 3 Homolog (PARD3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Partitioning Defective 3 Homolog (PARD3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Partitioning Defective 3 Homolog (PARD3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Partitioning Defective 3 Homolog (PARD3) ELISA Kit Customized Service Offer
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