≡

PTPRF Interacting Protein Binding Protein 1 (PPFIBP1)

[Edit]

L2; hSGT2; hSgt2p; Liprin-Beta-1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1

PTPRF Interacting Protein Binding Protein 1 (PPFIBP1)
CCC M054
HGNC 9249
MGI 1914783
PubMed 23957430
RGD 1310010
UniProt Q86W92
Wiki PPFIBP1
PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for PTPRF Interacting Protein Binding Protein 1 (PPFIBP1) ELISA Kit Customized Service Offer
  1. "Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins."J. Biol. Chem. 273:15611-15620(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1)."J. Biol. Chem. 277:5229-5235(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]