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RecQ Protein Like Protein (RECQL)

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RECQL1; RecQ1; ATP-Dependent DNA Helicase Q1; DNA helicase, RecQ-like type 1

RecQ Protein Like Protein (RECQL)
CCC M122
HGNC 9948
MGI 103021
PubMed 17158923
RGD 1311071
UniProt P46063
Wiki RECQL
RECQL is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.
RECQL gene was regionalized to 12p12-p11. The corresponding mouse gene, Recql, was mapped to the telomeric region of mouse chromosome 6 by analysis of DNA from an interspecific cross.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RecQ Protein Like Protein (RECQL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RecQ Protein Like Protein (RECQL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RecQ Protein Like Protein (RECQL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RecQ Protein Like Protein (RECQL) CLIA Kit Customized Service Offer
n/a ELISA Kit for RecQ Protein Like Protein (RECQL) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RecQ Protein Like Protein (RECQL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RecQ Protein Like Protein (RECQL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RecQ Protein Like Protein (RECQL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RecQ Protein Like Protein (RECQL) CLIA Kit Customized Service Offer
n/a ELISA Kit for RecQ Protein Like Protein (RECQL) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RecQ Protein Like Protein (RECQL) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RecQ Protein Like Protein (RECQL) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RecQ Protein Like Protein (RECQL) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RecQ Protein Like Protein (RECQL) CLIA Kit Customized Service Offer
n/a ELISA Kit for RecQ Protein Like Protein (RECQL) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ."J. Biol. Chem. 269:29838-29845(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12."Nucleic Acids Res. 22:4566-4573(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Purification of two DNA-dependent adenosinetriphosphatases having DNA helicase activity from HeLa cells and comparison of the properties of the two enzymes."J. Biochem. 115:523-531(1994) [PubMed] [Europe PMC] [Abstract]
  7. "RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination."J. Biol. Chem. 280:28085-28094(2005) [PubMed] [Europe PMC] [Abstract]
  8. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]