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RNA Exonuclease 4 Homolog (REXO4)

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XPMC2; XPMC2H; REX4; Xenopus Prevents Mitotic Catatrophe 2 Homolog

RNA Exonuclease 4 Homolog (REXO4)
CCC M135
HGNC 12820
MGI 2684957
PubMed 9325058
RGD 1306220
UniProt Q9GZR2
Wiki REXO4
XPMC2 is a Xenopus gene identified on the basis of its ability to correct a mitotic defect in S. pombe. Using an exon trapping strategy, Kwiatkowska et al. (1997) identified a human homolog of XPMC2 within a BAC from chromosomal region 9q34. The gene, which they designated XPMC2H, encodes a predicted 422-amino acid protein. Like the Xenopus protein, XPMC2H is a basic protein, with a pI of 10.6, and contains a nuclear localization signal and potential CDC2 kinase sites. The 2 protein sequences are 52% identical.
The XPMC2H gene contains 8 exons.Kwiatkowska et al. (1997) mapped the XPMC2H gene to chromosome 9q34.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Exonuclease 4 Homolog (REXO4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Exonuclease 4 Homolog (REXO4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Exonuclease 4 Homolog (REXO4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Exonuclease 4 Homolog (REXO4) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Exonuclease 4 Homolog (REXO4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Exonuclease 4 Homolog (REXO4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Exonuclease 4 Homolog (REXO4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Exonuclease 4 Homolog (REXO4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Exonuclease 4 Homolog (REXO4) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Exonuclease 4 Homolog (REXO4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Exonuclease 4 Homolog (REXO4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Exonuclease 4 Homolog (REXO4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Exonuclease 4 Homolog (REXO4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Exonuclease 4 Homolog (REXO4) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Exonuclease 4 Homolog (REXO4) ELISA Kit Customized Service Offer
  1. "Human XPMC2H: cDNA cloning, mapping to 9q34, genomic structure, and evaluation as TSC1."Genomics 44:350-354(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity."J. Biol. Chem. 275:34306-34313(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Functional proteomic analysis of human nucleolus."Mol. Biol. Cell 13:4100-4109(2002) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]