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Synembryn B (SYNB)

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RIC8B; hSyn; RIC8; Resistance To Inhibitors Of Cholinesterase 8 Homolog B; Brain synembryn

Synembryn B (SYNB)
CCC M148
HGNC 25555
MGI 2682307
RGD 631419
UniProt Q9NVN3
The deduced 520-amino acid rat protein shares 86% identity with the deduced 536-amino acid human protein over the first 483 amino acids; their C termini are completely divergent. RIC8B shares 40% amino acid identity with mouse synembryn (RIC8A).
Carbachol, a cholinergic agonist, induced the reversible translocation of fluorescence-tagged RIC8B from the cytosol to the plasma membrane of human neuroblastoma cells. In rat pheochromocytoma cells and human neuroblastoma cells, treatment with carbachol led to the colocalization of RIC8B with plasma membrane GNAQ, and treatment with isoproterenol, a beta-adrenergic agonist, led to the colocalization of RIC8B with plasma membrane GNAS.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synembryn B (SYNB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synembryn B (SYNB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synembryn B (SYNB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synembryn B (SYNB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synembryn B (SYNB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synembryn B (SYNB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synembryn B (SYNB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synembryn B (SYNB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synembryn B (SYNB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synembryn B (SYNB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Synembryn B (SYNB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Synembryn B (SYNB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Synembryn B (SYNB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Synembryn B (SYNB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Synembryn B (SYNB) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol."J. Cell. Physiol. 195:151-157(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]