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Superkiller Viralicidic Activity 2 Like Protein (SKIV2L)

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HLP; 170A; DDX13; SKI2; SKI2W; SKIV2; Helicase-like protein

Superkiller Viralicidic Activity 2 Like Protein (SKIV2L)
CCC M235
HGNC 10898
MGI 1099835
PubMed 22444670
RGD 1303059
UniProt Q15477
Wiki SKIV2L
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.
SKIV2L encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) CLIA Kit Customized Service Offer
n/a ELISA Kit for Superkiller Viralicidic Activity 2 Like Protein (SKIV2L) ELISA Kit Customized Service Offer
  1. "Identification and characterization of a human cDNA homologous to yeast SKI2."Genomics 25:660-666(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family."Nucleic Acids Res. 23:2120-2126(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B)."Genomics 36:240-251(1996) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The human PAF complex coordinates transcription with events downstream of RNA synthesis."Genes Dev. 19:1668-1673(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  14. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  16. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  17. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
  18. "SKIV2L mutations cause syndromic diarrhea, or trichohepatoenteric syndrome."Am. J. Hum. Genet. 90:689-692(2012) [PubMed] [Europe PMC] [Abstract]