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Sialyltransferase 9 (SIAT9)

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ST3GAL5; SIATGM3S; ST3GalV; Ganglioside GM3 synthase; Lactosylceramide Alpha-2,3-Sialyltransferase; ST3 Beta Galactoside Alpha-2,3-Sialyltransferase 5

Sialyltransferase 9 (SIAT9)
CCC M295
HGNC 10872
MGI 1339963
PubMed 24026681
RGD 620875
UniProt Q9UNP4
Wiki ST3GAL5
Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate.
The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. Ubiquitous. High expression in brain, skeletal muscle, placenta, and testis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sialyltransferase 9 (SIAT9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sialyltransferase 9 (SIAT9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sialyltransferase 9 (SIAT9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sialyltransferase 9 (SIAT9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sialyltransferase 9 (SIAT9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sialyltransferase 9 (SIAT9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sialyltransferase 9 (SIAT9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sialyltransferase 9 (SIAT9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sialyltransferase 9 (SIAT9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sialyltransferase 9 (SIAT9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sialyltransferase 9 (SIAT9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sialyltransferase 9 (SIAT9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sialyltransferase 9 (SIAT9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sialyltransferase 9 (SIAT9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sialyltransferase 9 (SIAT9) ELISA Kit Customized Service Offer
  1. "Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthase."J. Biol. Chem. 273:31652-31655(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and expression of ceramide galactosyltransferases. Comparison with other glycosyltransferases."Thesis (1999), Medical College of Viriginia, United States
  3. "Human GM3 synthase: a new mRNA variant encodes an NH2-terminal extended form of the protein."Biochim. Biophys. Acta 1759:348-358(2006) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase."Nat. Genet. 36:1225-1229(2004) [PubMed] [Europe PMC] [Abstract]