≡

Staufen Homolog 2 (STAU2)

[Edit]

Double-stranded RNA-binding protein Staufen homolog 2

Staufen Homolog 2 (STAU2)
CCC M313
HGNC 11371
MGI 1352508
PubMed 12140260
RGD 621479
UniProt Q9NUL3
Wiki STAU2
Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Staufen Homolog 2 (STAU2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Staufen Homolog 2 (STAU2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Staufen Homolog 2 (STAU2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Staufen Homolog 2 (STAU2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Staufen Homolog 2 (STAU2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Staufen Homolog 2 (STAU2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Staufen Homolog 2 (STAU2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Staufen Homolog 2 (STAU2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Staufen Homolog 2 (STAU2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Staufen Homolog 2 (STAU2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Staufen Homolog 2 (STAU2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Staufen Homolog 2 (STAU2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Staufen Homolog 2 (STAU2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Staufen Homolog 2 (STAU2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Staufen Homolog 2 (STAU2) ELISA Kit Customized Service Offer
  1. "Identification of a novel homolog of the Drosophila staufen protein in the chromosome 8q13-q21.1 region."Genomics 62:113-118(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Staufen2 isoforms localize to the somatodendritic domain of neurons and interact with different organelles."J. Cell Sci. 115:3285-3295(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs."RNA 15:104-115(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  15. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]