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Tumor Suppressing Subtransferable Candidate 1 (TSSC1)

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Tumor-suppressing STF cDNA 1 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein

Tumor Suppressing Subtransferable Candidate 1 (TSSC1)
CCC M407
HGNC 12383
MGI 1289332
PubMed 9403053
RGD 1305817
UniProt Q53HC9
Wiki TSSC1
TSSC1 has been reported as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene may reside on chromosome 2 rather than chromosome 11.
Hu et al. (1997) identified TSSC1 within a region of chromosome 11 associated with tumor suppression. The deduced 387-amino acid protein shows homology to RBBP4 and Drosophila Caf1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Suppressing Subtransferable Candidate 1 (TSSC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Suppressing Subtransferable Candidate 1 (TSSC1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Suppressing Subtransferable Candidate 1 (TSSC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Suppressing Subtransferable Candidate 1 (TSSC1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Tumor Suppressing Subtransferable Candidate 1 (TSSC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Tumor Suppressing Subtransferable Candidate 1 (TSSC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Tumor Suppressing Subtransferable Candidate 1 (TSSC1) ELISA Kit Customized Service Offer
  1. "A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes."Genomics 46:9-17(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]