SMEK Homolog 1, Suppressor Of Mek1 (SMEK1)
[Edit]FLFL1; smk1; PP4R3A; Serine/threonine-protein phosphatase 4 regulatory subunit 3A
PP4R3SMEK1 and SMEK2 contain several regions conserved in Dictyostelium, including a putative N-terminal Enabled/VASP homology-1 (EVH1) domain, a central domain of unknown function, and a C-terminal stretch of acidic residues followed by basic residues.The deduced 820-amino acid PP4R3-alpha shares 67% amino acid identity with PP4R3-beta (SMEK2). It contains an N-terminal domain that is similar to the RAN-binding domain of RANBP1 and to pleckstrin homology domains.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SMEK Homolog 1, Suppressor Of Mek1 (SMEK1) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity."Mol. Cell. Proteomics 4:1725-1740(2005) [PubMed] [Europe PMC] [Abstract]
- "Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases."Int. J. Biochem. Cell Biol. 40:2315-2332(2008) [PubMed] [Europe PMC] [Abstract]
- "A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication."Mol. Cell 31:33-46(2008) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]