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Ras Related C3 Botulinum Toxin Substrate 1 (Rac1)

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TC-25; p21-Rac1; MIG5; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1

Ras Related C3 Botulinum Toxin Substrate 1 (Rac1)
CCC M427
HGNC 9801
MGI 97845
PubMed 22407364
RGD 619755
UniProt P63000
Wiki Rac1
Rac1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. This mutant did bind to POR1 and it induced membrane ruffling and transformation. A second RAC mutant, which bound PAK but not POR1, induced JNK activation but was defective in inducing membrane ruffling and transformation. The authors concluded that the effects of RAC on the JNK cascade and on actin polymerization and cell proliferation are mediated by distinct effector functions that diverge at the level of RAC itself.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM427Hu01 Recombinant Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAM427Hu21 Monoclonal Antibody to Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) WB; IHC; ICC; IP.
PAM427Hu01 Polyclonal Antibody to Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) WB; IHC; ICC; IP.
Assay Kits SEM427Hu ELISA Kit for Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCM427Hu CLIA Kit for Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM427Mu01 Recombinant Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Polyclonal Antibody Customized Service Offer
Assay Kits SEM427Mu ELISA Kit for Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM427Ra01 Recombinant Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM427Ra01 Polyclonal Antibody to Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) WB; IHC; ICC; IP.
MAM427Ra21 Monoclonal Antibody to Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) WB; IHC; ICC; IP.
Assay Kits SEM427Ra ELISA Kit for Ras Related C3 Botulinum Toxin Substrate 1 (Rac1) Enzyme-linked immunosorbent assay for Antigen Detection.
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  60. "Multiple factors confer specific Cdc42 and Rac protein activation by dedicator of cytokinesis (DOCK) nucleotide exchange factors."J. Biol. Chem. 286:25341-25351(2011) [PubMed] [Europe PMC] [Abstract]