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DAZ Interacting Protein 3, Zinc Finger (DZIP3)

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hRUL138; Human RNA-Binding Ubiquitin Ligase Of 138 kDa; E3 ubiquitin-protein ligase DZIP3

DAZ Interacting Protein 3, Zinc Finger (DZIP3)
CCC M533
HGNC 30938
MGI 1917433
PubMed 24326307
RGD 1563278
UniProt Q86Y13
By sequencing clones obtained from a size-fractionated brain cDNA library, Ishikawa et al. (1998) cloned DZIP3, which they designated KIAA0675. The deduced 1,208-amino acid protein shares weak homology with tetratricopeptide repeat protein D (TTC3). RT-PCR detected ubiquitous DZIP3 expression, with highest levels in testis, skeletal muscle, ovary, and kidney.
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DAZ Interacting Protein 3, Zinc Finger (DZIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DAZ Interacting Protein 3, Zinc Finger (DZIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DAZ Interacting Protein 3, Zinc Finger (DZIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DAZ Interacting Protein 3, Zinc Finger (DZIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DAZ Interacting Protein 3, Zinc Finger (DZIP3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DAZ Interacting Protein 3, Zinc Finger (DZIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DAZ Interacting Protein 3, Zinc Finger (DZIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DAZ Interacting Protein 3, Zinc Finger (DZIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DAZ Interacting Protein 3, Zinc Finger (DZIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DAZ Interacting Protein 3, Zinc Finger (DZIP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant DAZ Interacting Protein 3, Zinc Finger (DZIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to DAZ Interacting Protein 3, Zinc Finger (DZIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to DAZ Interacting Protein 3, Zinc Finger (DZIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for DAZ Interacting Protein 3, Zinc Finger (DZIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for DAZ Interacting Protein 3, Zinc Finger (DZIP3) ELISA Kit Customized Service Offer
  1. "hRUL138, a novel human RNA-binding RING-H2 ubiquitin-protein ligase."J. Cell Sci. 116:605-616(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins."Proc. Natl. Acad. Sci. U.S.A. 100:538-543(2003) [PubMed] [Europe PMC] [Abstract]