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P Antigen Family, Member 2 (PAGE2)

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GAGEC2; GAGEE2; G Antigen Family C2; Prostate-associated gene 2 protein

P Antigen Family, Member 2 (PAGE2)
CCC M670
HGNC 31804
UniProt Q7Z2X7
Many human tumors express antigens that are recognized in vitro by cytolytic T lymphocytes (CTLs) derived from the tumor-bearing patient. The MAGE (melanoma-specific antigen) and GAGE (G antigen) gene family members encode such antigens. Chen et al. (1998) manipulated the androgen-sensitive, nontumorigenic, prostate-specific antigen (PSA)-secreting cell line LNCaP in vivo to produce 3 cell sublines that were progressively more tumorigenic, metastatic, and androgen-insensitive.
By searching an EST database for sequences similar to PAGE1, Brinkmann et al. (1998) identified PAGE2, which appeared to be expressed primarily in testis.Hartz (2008) mapped the PAGE2 gene to chromosome Xp11.21 based on an alignment of the PAGE2 sequence with the genomic sequence (build 36.1).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant P Antigen Family, Member 2 (PAGE2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to P Antigen Family, Member 2 (PAGE2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to P Antigen Family, Member 2 (PAGE2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for P Antigen Family, Member 2 (PAGE2) CLIA Kit Customized Service Offer
n/a ELISA Kit for P Antigen Family, Member 2 (PAGE2) ELISA Kit Customized Service Offer
  1. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]