≡

N-Acetyltransferase 8 Like Protein (NAT8L)

[Edit]

Hcml3; CML3; NAA synthetase; N-acetylaspartate synthetase; Camello-like protein 3

N-Acetyltransferase 8 Like Protein (NAT8L)
CCC N064
HGNC 26742
MGI 2447776
PubMed 24155240
RGD 1305719
UniProt Q8N9F0
By searching an EST database for sequences similar to Xenopus camello, Popsueva et al. (2001) identified NAT8L, which they called CML3. The deduced 144-amino acid protein has a hydrophobic domain in its N-terminal half and 3 motifs characteristic of an acetyltransferase in its C-terminal half. Hartz (2006) mapped the NAT8L gene to chromosome 4p16.3 based on an alignment of the NAT8L sequence with the genomic sequence (build 36.1).
N-acetyltransferase is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPN064Hu01 Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAN064Hu21 Monoclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) WB; IHC; ICC; IP.
PAN064Hu01 Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) WB
Assay Kits SEN064Hu ELISA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) CLIA Kit Customized Service Offer
n/a ELISA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant N-Acetyltransferase 8 Like Protein (NAT8L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to N-Acetyltransferase 8 Like Protein (NAT8L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) CLIA Kit Customized Service Offer
n/a ELISA Kit for N-Acetyltransferase 8 Like Protein (NAT8L) ELISA Kit Customized Service Offer
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation."Nat. Biotechnol. 22:707-716(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Overexpression of camello, a member of a novel protein family, reduces blastomere adhesion and inhibits gastrulation in Xenopus laevis."Dev. Biol. 234:483-496(2001) [PubMed] [Europe PMC] [Abstract]
  6. "Evidence for mitochondrial and cytoplasmic N-acetylaspartate synthesis in SH-SY5Y neuroblastoma cells."Neurochem. Int. 55:219-225(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia."Biochem. J. 425:127-136(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS."Brain Res. 1335:1-13(2010) [PubMed] [Europe PMC] [Abstract]