tRNA-yW Synthesizing Protein 2 (TYW2)
[Edit]TRMT12; Trm12; tRNA Methyltransferase 12 Homolog; tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase; tRNA wybutosine-synthesizing protein 2 homolog
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tRNA wybutosine-synthesizing protein 2 homolog is a protein encoded by the TRMT12 gene.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis.
By searching databases for homologs of yeast Trm12, Kalhor et al. (2005) identified human TRMT12.The International Radiation Hybrid Mapping Consortium mapped the TRMT12 gene to chromosome 8
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant tRNA-yW Synthesizing Protein 2 (TYW2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to tRNA-yW Synthesizing Protein 2 (TYW2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to tRNA-yW Synthesizing Protein 2 (TYW2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for tRNA-yW Synthesizing Protein 2 (TYW2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for tRNA-yW Synthesizing Protein 2 (TYW2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant tRNA-yW Synthesizing Protein 2 (TYW2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to tRNA-yW Synthesizing Protein 2 (TYW2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to tRNA-yW Synthesizing Protein 2 (TYW2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for tRNA-yW Synthesizing Protein 2 (TYW2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for tRNA-yW Synthesizing Protein 2 (TYW2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant tRNA-yW Synthesizing Protein 2 (TYW2) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to tRNA-yW Synthesizing Protein 2 (TYW2) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to tRNA-yW Synthesizing Protein 2 (TYW2) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for tRNA-yW Synthesizing Protein 2 (TYW2) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for tRNA-yW Synthesizing Protein 2 (TYW2) | ELISA Kit Customized Service Offer |
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Structure-function analysis of human TYW2 enzyme required for the biosynthesis of a highly modified Wybutosine (yW) base in phenylalanine-tRNA."PLoS ONE 7:E39297-E39297(2012) [PubMed] [Europe PMC] [Abstract]