Adropin (AD)

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ENHO; UNQ470; Energy Homeostasis Associated Protein

Adropin (AD)
Adropin, a recently described endogenous neuroendocrine peptide, has been suggested to play a critical role in modulating normal physiological processes and maintaining metabolic homeostasis. Adropin (10 ng/mL) caused a marked 10-fold increase in endothelial cell migration and proliferation and significantly increased capillary-like endothelial cell sprouting and tube formation (p<0.001).
In mice,the liver produces a protein called adropin, which rises in response to high-fat foods and falls after fasting. The protein seems to play a role in governing the activity of other metabolic genes, particularly those involved in the production of lipids from carbohydrates. Studies of the protein in obese animals suggest that it also plays a role in insulin response and in preventing the buildup of fat in the liver.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPN251Hu01 Recombinant Adropin (AD) Positive Control; Immunogen; SDS-PAGE; WB.
CPN251Hu21 OVA Conjugated Adropin (AD) Immunogen; SDS-PAGE; WB.
Antibodies PAN251Hu01 Polyclonal Antibody to Adropin (AD) WB; IHC; ICC; IP.
MAN251Hu21 Monoclonal Antibody to Adropin (AD) WB; IHC; ICC; IP.
Assay Kits SEN251Hu ELISA Kit for Adropin (AD) Enzyme-linked immunosorbent assay for Antigen Detection.
HEN251Hu High Sensitive ELISA Kit for Adropin (AD) Enzyme-linked immunosorbent assay for Antigen Detection.
CEN251Hu ELISA Kit for Adropin (AD) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPN251Mu01 Recombinant Adropin (AD) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAN251Mu01 Polyclonal Antibody to Adropin (AD) WB; IHC; ICC; IP.
Assay Kits SEN251Mu ELISA Kit for Adropin (AD) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism."Cell Metab. 8:468-481(2008) [PubMed] [Europe PMC] [Abstract]