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Flavin Adenine Dinucleotide Synthetase 1 (FLAD1)

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PP591; FAD1; FAD pyrophosphorylase; FMN adenylyltransferase; Molybdenum cofactor biosynthesis protein-like region

Flavin Adenine Dinucleotide Synthetase 1 (FLAD1)
CCC N275
HGNC 24671
MGI 2443030
UniProt Q8NFF5
FAD synthetase (EC 2.7.7.2) catalyzes the adenylation of flavin mononucleotide (FMN) into the redox cofactor FAD.FLAD1 encodes 2 alternatively spliced transcripts, which the authors named FADS1 and FADS2. FADS1 encodes a 587-amino acid protein with a predicted molecular mass of 65.3 kD, and FADS2 encodes a 490-amino acid protein with a predicted molecular mass of 54.2 kD. FADS2 uses a downstream start codon and thus lacks an N-terminal region present in FADS1.
Analysis using protein prediction programs showed that both FLAD1 isoforms have a predicted cytoplasmic location, although FADS1 also contains an N-terminal mitochondrial targeting sequence.both FLAD1 isoforms possess MgCl2-dependent FAD synthetase activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Flavin Adenine Dinucleotide Synthetase 1 (FLAD1) ELISA Kit Customized Service Offer
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  10. "Mitochondrial localization of human FAD synthetase isoform 1."Mitochondrion 10:263-273(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]