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RAB GTPase Activating Protein 1 Like Protein (RABGAP1L)

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HHL; TBC1D18

RAB GTPase Activating Protein 1 Like Protein (RABGAP1L)
CCC N278
HGNC 24663
MGI 1352507
PubMed 23335107
RGD 1304620
UniProt Q5R372
RABGAP1L expression was upregulated in esophageal squamous cell carcinomas compared with matched normal esophageal epithelial tissue. In particular, RABGAP1L expression was upregulated in esophageal tumors showing nodal invasion.
The deduced 298-amino acid protein contains a PTB domain and shares homology with the N terminus of human GAPCENA (RABGAP1). Northern blot analysis detected several Rabgap1l transcripts expressed in a tissue-specific manner. In situ hybridization of day-14.5 embryos revealed expression in heart and liver.The deduced protein contains 370 amino acids. SDS-PAGE detected RABGAP1L at an apparent molecular mass of about 50 kD.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB GTPase Activating Protein 1 Like Protein (RABGAP1L) ELISA Kit Customized Service Offer
  1. "Genes preferentially expressed in precancerous lesion of HCC."Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
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  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract], Colon and Testis.
  6. "NovelFam3000 -- uncharacterized human protein domains conserved across model organisms."BMC Genomics 7:48-48(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Transcriptional gene expression profile of human esophageal squamous cell carcinoma."Genomics 81:481-488(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Reduced KIAA0471 mRNA expression in Alzheimer's patients: a new candidate gene product linked to the disease?"Hum. Mol. Genet. 13:2607-2612(2004) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "Crystal structure of the RabGAP domain of the RABGAP1L protein."Submitted (JUL-2009) to the PDB data bank