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Melanoma Inhibitory Activity Protein 3 (MIA3)

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TANGO; C219 Reactive Peptide; Transport and Golgi organization protein 1

Melanoma Inhibitory Activity Protein 3 (MIA3)
CCC N378
HGNC 24008
MGI 2443183
PubMed 21606205
UniProt Q5JRA6
TANGO expression was reduced in human melanoma tissues and in melanoma cell lines. The reduction was greater in distant tissue metastases and in cell lines derived from malignant melanomas. Functional assays revealed that induced TANGO expression resulted in significantly decreased cell motility and invasive potential. In contrast, knockdown of TANGO expression via small interfering RNA promoted cell invasion and migration.The deduced 125-amino acid protein encodes a hydrophobic secretory signal sequence. RT-PCR analysis and RNA dot-blot analysis revealed widespread TANGO expression, with highest levels in prostate, testis, heart, and liver, and little to none in spleen, bone marrow, and peripheral blood mononuclear cells. In situ hybridization of mouse embryos revealed very early and widespread Tango expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Inhibitory Activity Protein 3 (MIA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Inhibitory Activity Protein 3 (MIA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Inhibitory Activity Protein 3 (MIA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Inhibitory Activity Protein 3 (MIA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Inhibitory Activity Protein 3 (MIA3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Inhibitory Activity Protein 3 (MIA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Inhibitory Activity Protein 3 (MIA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Inhibitory Activity Protein 3 (MIA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Inhibitory Activity Protein 3 (MIA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Inhibitory Activity Protein 3 (MIA3) ELISA Kit Customized Service Offer
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