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cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2)

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BBF2H7; BBF2 human homolog on chromosome 7

cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2)
CCC N395
HGNC 23720
MGI 2442695
PubMed 21536545
RGD 1306040
UniProt Q70SY1
CREB3L2 is a member of the old astrocyte specifically induced substance (OASIS) DNA binding and basic leucine zipper dimerization (bZIP) family of transcription factors, which includes CREB3 and CREB4.
CREB3L2 residues 291 to 356 constitute the consensus bZIP domain found in other OASIS transcription factor family members. A conserved leucine zipper motif extends from residues 321 to 359, and an alpha-helical transmembrane domain stretches from residues 376 to 397. RT-PCR analysis demonstrated CREB3L2 expression in most tissues examined, with strongest expression in adult human placenta, lung, spleen, and intestine, and weakest expression in heart, brain, skeletal muscle, thymus, colon, and leukocytes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) CLIA Kit Customized Service Offer
n/a ELISA Kit for cAMP Responsive Element Binding Protein 3 Like Protein 2 (CREB3L2) ELISA Kit Customized Service Offer
  1. "Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma."Hum. Mol. Genet. 12:2349-2358(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma."Genes Chromosomes Cancer 40:218-228(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer."Mol. Cell. Biol. 27:1716-1729(2007) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Activation of OASIS family, ER stress transducers, is dependent on its stabilization."Cell Death Differ. 19:1939-1949(2012) [PubMed] [Europe PMC] [Abstract]