Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5)

[Edit]

BE37; YMO1

Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5)
The deduced EPB41L5 and moe proteins share 61% overall sequence identity and 87% identity in the N terminus. Both proteins contain a conserved FERM domain present in members of the EPB41 family of cytoskeletal proteins. RT-PCR ELISA detected expression in all tissues tested, with highest expression in kidney, ovary, and brain.
Epb41L5 binds to conserved motifs in Crb1, Crb2, Crb3, and Mpp5, and is a component of the Crumbs polarity complex first identified in Drosophila. They concluded that EPB41L5 is likely to be important in cell polarity processes in many epithelial-derived tissues in addition to the retina.the Yrt/Cora group is essential for epithelial polarity during organogenesis but not when epithelial polarity is first established or during terminal differentiation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Erythrocyte Membrane Protein Band 4.1 Like Protein 5 (EPB41L5) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
  4. "FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex."Exp. Cell Res. 313:3959-3970(2007) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]