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Keratin Associated Protein 1-4 (KRTAP1-4)

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KAP1.4; High sulfur keratin-associated protein 1.4

Keratin Associated Protein 1-4 (KRTAP1-4)
CCC N680
HGNC 18904
PubMed 12895003
UniProt P0C5Y4
The main structural proteins of mammalian hair fiber are the hair keratins and the keratin-associated proteins (KAPs), which form a rigid and resistant hair shaft through extensive disulfide bond crosslinking with the abundant cysteines of hair keratins.KRTAP1-4 gene is about 1.0 kb long and consists of a single exon.
The deduced 121-amino acid protein has a calculated molecular mass of 12.3 kD. KAP1.4 is classified as a high sulfur protein owing to a cysteine content of 24.8 mol %. It contains 2 unique motifs conserved among KAP1 family members, several characteristic pentapeptide repeats, and a 20-amino acid subdomain that was conserved among KAP1 family members in all species examined. KAP1.4 lacks an amino-terminal motif common to other members of the KAP1 family.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Keratin Associated Protein 1-4 (KRTAP1-4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Keratin Associated Protein 1-4 (KRTAP1-4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Keratin Associated Protein 1-4 (KRTAP1-4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Keratin Associated Protein 1-4 (KRTAP1-4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Keratin Associated Protein 1-4 (KRTAP1-4) ELISA Kit Customized Service Offer
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21."J. Biol. Chem. 276:19440-19451(2001) [PubMed] [Europe PMC] [Abstract]