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Cytochrome P450 4F12 (CYP4F12)

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CYPIVF12; Cytochrome P450 Family 4 Subfamily F Polypeptide 12

Cytochrome P450 4F12 (CYP4F12)
CCC N686
HGNC 18857
MGI 1927669
PubMed 11162607
RGD 70926
UniProt Q9HCS2
Wiki CYP4F12
CYP4F12 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid; however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19.
CYP4F12 catalyzed the oxidation of the omega-side chains of 2 stable prostaglandin (PG) H2 analogs, 11,9-epoxymethano-PGH(2) and 9,11-diazo-15 deoxy-PGH(2). It oxidized the omega-side chain of leukotriene B4 (LTB4) poorly.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome P450 4F12 (CYP4F12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome P450 4F12 (CYP4F12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome P450 4F12 (CYP4F12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome P450 4F12 (CYP4F12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome P450 4F12 (CYP4F12) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome P450 4F12 (CYP4F12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome P450 4F12 (CYP4F12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome P450 4F12 (CYP4F12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome P450 4F12 (CYP4F12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome P450 4F12 (CYP4F12) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome P450 4F12 (CYP4F12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome P450 4F12 (CYP4F12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome P450 4F12 (CYP4F12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome P450 4F12 (CYP4F12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome P450 4F12 (CYP4F12) ELISA Kit Customized Service Offer
  1. "cDNA cloning and expression of CYP4F12, a novel human cytochrome P450."Biochem. Biophys. Res. Commun. 280:892-897(2001) [PubMed] [Europe PMC] [Abstract]
  2. "cDNA cloning and expression of a novel cytochrome p450 (cyp4f12) from human small intestine."Biochem. Biophys. Res. Commun. 280:1135-1141(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]