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Kelch Like Protein 8 (KLHL8)

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Kelch Like Protein 8 (KLHL8)
CCC N717
HGNC 18644
MGI 2179430
PubMed 12168954
RGD 1304685
UniProt Q9P2G9
Wiki KLHL8
By sequencing clones obtained from a size-fractionated fetal brain cDNA library, Nagase et al. (2000) cloned KLHL8, which they designated KIAA1378. The mRNA contains a repetitive element in its 3-prime UTR, and the deduced 451-amino acid protein shares 36% identity with the actin-binding protein MAYVEN (KLHL2). RT-PCR ELISA detected highest expression in adult brain, liver, skeletal muscle, kidney, and ovary, and in several specific brain regions, predominantly amygdala and thalamus. Moderate expression was detected in all other adult and fetal tissues examined.
Hartz (2008) mapped the KLHL8 gene to chromosome 4q22.1 based on an alignment of the KLHL8 sequence with the genomic sequence (build 36.1).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kelch Like Protein 8 (KLHL8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kelch Like Protein 8 (KLHL8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kelch Like Protein 8 (KLHL8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kelch Like Protein 8 (KLHL8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kelch Like Protein 8 (KLHL8) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kelch Like Protein 8 (KLHL8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kelch Like Protein 8 (KLHL8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kelch Like Protein 8 (KLHL8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kelch Like Protein 8 (KLHL8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kelch Like Protein 8 (KLHL8) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kelch Like Protein 8 (KLHL8) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kelch Like Protein 8 (KLHL8) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kelch Like Protein 8 (KLHL8) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kelch Like Protein 8 (KLHL8) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kelch Like Protein 8 (KLHL8) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Control of rapsyn stability by the CUL-3-containing E3 ligase complex."J. Biol. Chem. 284:8195-8206(2009) [PubMed] [Europe PMC] [Abstract]
  7. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]