≡

Rho GTPase Activating Protein 20 (ARHGAP20)

[Edit]

Rho GTPase Activating Protein 20 (ARHGAP20)
CCC N754
HGNC 18357
MGI 2445175
PubMed 21500311
RGD 1303160
UniProt Q9P2F6
The deduced 1,194-amino acid protein contains a pleckstrin homology (PH) domain. RT-PCR ELISA detected intermediate ARHGAP20 expression in brain, testis, ovary, and spinal cord and in all specific brain regions examined. Lower expression was detected in liver and fetal brain, and little to no expression was detected in other tissues examined.
Expression of ARHGAP20 was upregulated about 6-fold in 18 of 22 BCLL tumors examined compared with normal B cells. However, 2 cases with translocations affecting 1 copy of the ARHGAP20 gene, 1 case with monoallelic deletion of chromosome region 11q22-q23, and 1 case with no chromosome 11 deletion showed about 10-fold downregulation of ARHGAP20 expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 20 (ARHGAP20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 20 (ARHGAP20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 20 (ARHGAP20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 20 (ARHGAP20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 20 (ARHGAP20) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 20 (ARHGAP20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 20 (ARHGAP20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 20 (ARHGAP20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 20 (ARHGAP20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 20 (ARHGAP20) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho GTPase Activating Protein 20 (ARHGAP20) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho GTPase Activating Protein 20 (ARHGAP20) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho GTPase Activating Protein 20 (ARHGAP20) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho GTPase Activating Protein 20 (ARHGAP20) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho GTPase Activating Protein 20 (ARHGAP20) ELISA Kit Customized Service Offer
  1. "Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes."Genes Chromosomes Cancer 42:128-143(2005) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Identification and characterization of human KIAA1391 and mouse Kiaa1391 genes encoding novel RhoGAP family proteins with RA domain and ANXL repeats."Int. J. Oncol. 23:1471-1476(2003) [PubMed] [Europe PMC] [Abstract]