By sequencing clones obtained from a size-fractionated brain cDNA library, Nagase et al. (1999) cloned THSD7A, which they designated KIAA0960. The deduced 1,290-amino acid protein shares characteristics with proteins involved in cell signaling. RT-PCR ELISA detected low to moderate expression in all tissues and specific brain regions examined except skeletal muscle, where expression was absent.By radiation hybrid analysis, Nagase et al. (1999) mapped the THSD7A gene to chromosome 7.
The thrombospondins (TSP) are a family of multifunctional proteins. The family consists of thrombospondins 1-5 and can be divided into 2 subgroups: A, which contains TSP-1 and -2, and B, which contains TSP-3, -4 and -5.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEN909Hu | ELISA Kit for Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Enzyme-linked immunosorbent assay for Antigen Detection. |
AEN909Hu | ELISA Kit for Anti-Thrombospondin Type I Domain Containing Protein 7A Antibody (Anti-THSD7A) | Enzyme-linked immunosorbent assay for Antibody Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPN909Mu01 | Recombinant Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAN909Mu01 | Polyclonal Antibody to Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thrombospondin Type I Domain Containing Protein 7A (THSD7A) | ELISA Kit Customized Service Offer |
- "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
- "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
- "Soluble THSD7A is an N-glycoprotein that promotes endothelial cell migration and tube formation in angiogenesis."PLoS ONE 6:E29000-E29000(2011) [PubMed] [Europe PMC] [Abstract]