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Nucleoporin 43kDa (NUP43)

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p42; Nup107-160 subcomplex subunit Nup43

Nucleoporin 43kDa (NUP43)
CCC N977
HGNC 21182
MGI 1917162
PubMed 12196509
UniProt Q8NFH3
Wiki NUP43
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160.
NUP43 contains WD repeats and has a calculated molecular mass of about 42 kD. Fluorescence-tagged NUP43, transfected into HeLa cells, showed punctate nuclear rim localization typical of nucleoporins.NUP43 and several other WD-repeat nucleoporins are constituents of the Nup107-160 complex. All constituents of this complex were targeted to kinetochores from prophase to anaphase during mitosis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleoporin 43kDa (NUP43) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleoporin 43kDa (NUP43) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleoporin 43kDa (NUP43) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleoporin 43kDa (NUP43) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleoporin 43kDa (NUP43) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleoporin 43kDa (NUP43) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleoporin 43kDa (NUP43) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleoporin 43kDa (NUP43) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleoporin 43kDa (NUP43) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleoporin 43kDa (NUP43) ELISA Kit Customized Service Offer
  1. "Proteomic analysis of the mammalian nuclear pore complex."J. Cell Biol. 158:915-927(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis."Mol. Biol. Cell 15:3333-3344(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions."EMBO J. 26:1853-1864(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex."Proc. Natl. Acad. Sci. U.S.A. 104:3811-3816(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]