Triclosan (TCS)
Triclosan is an antibacterial and antifungal agent found in numerous consumer products. It is a polychloro phenoxy phenol. At in-use concentrations, triclosan acts as a biocide, with multiple cytoplasmic and membrane targets. At lower concentrations, however, triclosan appears bacteriostatic and is seen to target bacteria mainly by inhibiting fatty acid synthesis. Triclosan binds to bacterial enoyl-acyl carrier protein reductase enzyme (ENR), which is encoded by the gene FabI. This binding increases the enzyme's affinity for nicotinamide adenine dinucleotide (NAD+). This results in the formation of a stable ternary complex of ENR-NAD+-triclosan, which is unable to participate in fatty acid synthesis. Fatty acids are necessary for reproducing and building cell membranes. Humans do not have an ENR enzyme, and thus are not affected.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins CPO342Ge11 BSA Conjugated Triclosan (TCS) Immunogen; SDS-PAGE; WB.
CPO342Ge21 OVA Conjugated Triclosan (TCS) Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Triclosan (TCS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Triclosan (TCS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Triclosan (TCS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Triclosan (TCS) ELISA Kit Customized Service Offer