Psalmotoxin 1 (PcTX1)
Psalmotoxin (PcTx1) is a spider toxin from the venom of the Trinidad tarantula Psalmopoeus cambridgei. The psalmotoxin structure can be classified as an inhibitor cystine knot (ICK) protein. Many ion channel effectors from snail, spider, and scorpion venoms share a similar ICK structure, although they possess very different pharmalogical profiles. Among ICK toxins, psalmotoxin is the only peptide known to act on homomeric ASIC1 channels. Psalmotoxin is a 40-amino acid peptide, possessing 6 cysteines linked by three disulfide bridges. The three-dimensional structure consists of a compact disulfide-bonded core from which three loops and the N and C termini emerge. The main element of the structure is a three-stranded antiparallel β-sheet. Psalmotoxin can bind to a particular isoform of the Acid Sensing Ion Channel, the Acid Sensing Ion Channel 1 (ASIC1).

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Complete Antigen of Psalmotoxin 1 (PcTX1) Antigenic Transformation Customized Service Offer
Antibodies n/a Monoclonal Antibody to Psalmotoxin 1 (PcTX1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Psalmotoxin 1 (PcTX1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Psalmotoxin 1 (PcTX1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Psalmotoxin 1 (PcTX1) ELISA Kit Customized Service Offer