Canadine (CND)
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Canadine is a protoberberine alkaloid which can act as a calcium channel blocker. It is also one of the many alkaloids found in Corydalis Yanhuso plant from the Opium Poppy family.
Berberine is responsible for the activity of an extract of a commercial root sample of Hydrastis canadensis against multiply drug resistant Mycobacterium tuberculosis. Two new quinic acid feruloyl esters, compounds 2 and 3, have been isolated from the same source along with canadine, 8-oxotetrahydrothalifendine, and beta-hydrastine. These were found to be inactive. The structures of the new compounds were elucidated from spectral (1H, 13C, HMQC, HMBC, and H-H COSY) and chemical evidences.
Berberine is responsible for the activity of an extract of a commercial root sample of Hydrastis canadensis against multiply drug resistant Mycobacterium tuberculosis. Two new quinic acid feruloyl esters, compounds 2 and 3, have been isolated from the same source along with canadine, 8-oxotetrahydrothalifendine, and beta-hydrastine. These were found to be inactive. The structures of the new compounds were elucidated from spectral (1H, 13C, HMQC, HMBC, and H-H COSY) and chemical evidences.
Organism species: Pan-species (General)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Complete Antigen of Canadine (CND) | Antigenic Transformation Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Canadine (CND) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Canadine (CND) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Canadine (CND) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Canadine (CND) | ELISA Kit Customized Service Offer |