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F Protein Binding Protein 1 (FBP1)

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RAB14; Small GTP Binding Protein RAB14

F Protein Binding Protein 1 (FBP1)
CCC P093
HGNC 16524
MGI 1915615
PubMed 22039417
RGD 620881
UniProt P61106
Wiki FBP1
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes.RAB14 staining partially overlapped with markers for early and recycling endosomes, cis-Golgi, and trans-Golgi network. Immunogold labeling of normal rat kidney cells revealed membrane-bound Rab14 associated with multiple membrane and vesicular structures. Most Rab14 was associated with small tubulo-vesicular structures throughout the cytoplasm, with Golgi stack and associated vesicles, and with endoplasmic reticulum. A minor fraction was associated with endosomal vacuoles and the plasma membrane.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F Protein Binding Protein 1 (FBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F Protein Binding Protein 1 (FBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F Protein Binding Protein 1 (FBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F Protein Binding Protein 1 (FBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for F Protein Binding Protein 1 (FBP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F Protein Binding Protein 1 (FBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F Protein Binding Protein 1 (FBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F Protein Binding Protein 1 (FBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F Protein Binding Protein 1 (FBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for F Protein Binding Protein 1 (FBP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant F Protein Binding Protein 1 (FBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to F Protein Binding Protein 1 (FBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to F Protein Binding Protein 1 (FBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for F Protein Binding Protein 1 (FBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for F Protein Binding Protein 1 (FBP1) ELISA Kit Customized Service Offer
  1. "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning." Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
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  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
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  6. , Submitted (FEB-2006) to UniProtKB
  7. "Rab14 is part of the early endosomal clathrin-coated TGN microdomain."FEBS Lett. 580:5241-5246(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes."Traffic 12:407-420(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Rab14 and its exchange factor FAM116 link endocytic recycling and adherens junction stability in migrating cells."Dev. Cell 22:952-966(2012) [PubMed] [Europe PMC] [Abstract]
  12. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  13. "Structural basis of family-wide Rab GTPase recognition by rabenosyn-5."Nature 436:415-419(2005) [PubMed] [Europe PMC] [Abstract]
  14. "Crystal structure of human RAB14."Submitted (FEB-2009) to the PDB data bank