Ceramide Synthase 1 (CERS1)
[Edit]LAG1; UOG1; CerS1; LASS1; Longevity Assurance Homolog 1; LAG1 longevity assurance homolog 1
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LASS1 encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging.
This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.LASS1 protein contains a conserved 52-residue stretch termed the Lag1 motif, as well as a transmembrane domain.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ceramide Synthase 1 (CERS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ceramide Synthase 1 (CERS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ceramide Synthase 1 (CERS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ceramide Synthase 1 (CERS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ceramide Synthase 1 (CERS1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ceramide Synthase 1 (CERS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ceramide Synthase 1 (CERS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ceramide Synthase 1 (CERS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ceramide Synthase 1 (CERS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ceramide Synthase 1 (CERS1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Ceramide Synthase 1 (CERS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Ceramide Synthase 1 (CERS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Ceramide Synthase 1 (CERS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Ceramide Synthase 1 (CERS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Ceramide Synthase 1 (CERS1) | ELISA Kit Customized Service Offer |
- "Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure."Proc. Natl. Acad. Sci. U.S.A. 88:4250-4254(1991) [PubMed] [Europe PMC] [Abstract]
- "Homologs of the yeast longevity gene LAG1 in Caenorhabditis elegans and human."Genome Res. 8:1259-1272(1998) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]