≡

PTPRF Interacting Protein Binding Protein 2 (PPFIBP2)

[Edit]

Cclp1; Liprin-Beta-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2

PTPRF Interacting Protein Binding Protein 2 (PPFIBP2)
CCC P792
HGNC 9250
MGI 894649
PubMed 21207424
RGD 1565383
UniProt Q8ND30
PPFIBP2 belongs to the liprin-beta family. Members of the LAR family are transmembrane protein-tyrosine phosphatases (PTPases). The LIP1 protein (PPFIA1 has been shown to bind to the LAR membrane-distal D2 PTPase domain. Serra-Pages et al. (1998) carried out a yeast interaction trap screen using LIP1 as bait. They isolated a partial human fibroblast cDNA encoding a protein they called LIP-related protein (liprin)-beta-2. The predicted 783-amino acid polypeptide shares 51% sequence identity with liprin-beta-1. Liprins are multivalent proteins that form complex structures that act as scaffolds for the recruitment and anchoring of LAR family PTPases. Northern blot analysis revealed that the liprin-beta-2 gene is expressed broadly as a 3.9-kb mRNA. A second 5.1-kb transcript was observed in heart and skeletal muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for PTPRF Interacting Protein Binding Protein 2 (PPFIBP2) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins."J. Biol. Chem. 273:15611-15620(1998) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]