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Pepsinogen 4, Group I (PGA4)

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Pepsinogen A4; Pepsin A-4

Pepsinogen 4, Group I (PGA4)
CCC P801
HGNC 8886
PubMed 17257864
UniProt P0DJD7
PGA4 belongs to the peptidase A1 family. The predicted amino acid sequence of human pepsinogen consists of 373 residues and is 82% homologous with that of swine pepsinogen. The predicted sequence contains 15 amino acid residues at the NH2 end, showing that the protein is synthesized as a prepepsinogen. In human gastric mucosa, 2 immunologically distinct classes of pepsinogen are synthesized. PG1 is restricted to the corpus, while PG2 is found throughout the stomach as well as in the proximal duodenum. PG1 is found in serum and urine in a ratio of about 1 to 10. PG2 is present in serum and seminal fluid but only trace amounts are found in urine. Serum PG1 and PG2 apparently originate from the stomach in the main, because the levels are very low after gastrectomy. PG2 in seminal fluid probably originates from the prostate.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pepsinogen 4, Group I (PGA4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pepsinogen 4, Group I (PGA4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pepsinogen 4, Group I (PGA4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pepsinogen 4, Group I (PGA4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pepsinogen 4, Group I (PGA4) ELISA Kit Customized Service Offer
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