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Keratin 38 (KRT38)

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KRTHA8; K38; HHA8; HKA8; Keratin,Hair,Acidic 8; Keratin, type I cuticular Ha8

Keratin 38 (KRT38)
CCC P893
HGNC 6456
UniProt O76015
Wiki KRT38
KRTHA8 is expressed in the human hair follicle.the deduced KRTHA8 protein, which they called HA8, has 415 amino acids. The KRTHA8 gene contains 7 exons.The hair keratin genes range in size from 4.2 to 7.5 kb, and the genes are separated from each other by 5.5 to 18.4 kb; all are located within about 140 kb. Each gene is transcribed from the 5-prime to 3-prime direction. Based on sequence homologies, the genes can be grouped into 3 subclusters of tandemly arranged genes. The functional hair keratins and hypothetical HAA hair keratin share approximately 81% overall amino acid identity. Due to an almost completely identical head domain, KRTHA7 and KRTHA8 are 92.6% identical. The third subcluster, group C, consists of the structurally less related hair keratins KRTHA2, KRTHA5, and KRTHA6, which share about 70% amino acid identity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Keratin 38 (KRT38) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Keratin 38 (KRT38) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Keratin 38 (KRT38) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Keratin 38 (KRT38) CLIA Kit Customized Service Offer
n/a ELISA Kit for Keratin 38 (KRT38) ELISA Kit Customized Service Offer
  1. "Characterization of a 190-kilobase pair domain of human type I hair keratin genes."J. Biol. Chem. 273:26683-26691(1998) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain."Differentiation 72:527-540(2004) [PubMed] [Europe PMC] [Abstract]