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Histone Cluster 1, H1c (HIST1H1C)

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H1F2; H1.2; H1 Histone Family Member 2

Histone Cluster 1, H1c (HIST1H1C)
CCC Q033
HGNC 4716
MGI 1931526
PubMed 2759094
UniProt P16403
Wiki HIST1H1C
HIST1H1C is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.histone H1.2 was a cytochrome c-releasing factor that appeared in the cytoplasm after exposure of cells to x-ray irradiation. While all nuclear histone H1 forms were released into the cytoplasm in a p53 (TP53)-dependent manner after irradiation, only H1.2 induced cytochrome c release from isolated mitochondria in a BAK (BAK1)-dependent manner. Reducing H1.2 expression enhanced cellular resistance to apoptosis induced by x-ray irradiation or etoposide, but not that induced by other apoptotic stimuli.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ033Hu01 Recombinant Histone Cluster 1, H1c (HIST1H1C) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Histone Cluster 1, H1c (HIST1H1C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Histone Cluster 1, H1c (HIST1H1C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Histone Cluster 1, H1c (HIST1H1C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Histone Cluster 1, H1c (HIST1H1C) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Histone Cluster 1, H1c (HIST1H1C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Histone Cluster 1, H1c (HIST1H1C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Histone Cluster 1, H1c (HIST1H1C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Histone Cluster 1, H1c (HIST1H1C) CLIA Kit Customized Service Offer
n/a ELISA Kit for Histone Cluster 1, H1c (HIST1H1C) ELISA Kit Customized Service Offer
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  7. "Human spleen histone H1. Isolation and amino acid sequences of three minor variants, H1a, H1c, and H1d."J. Biochem. 106:844-857(1989) [PubMed] [Europe PMC] [Abstract]