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Cytochrome P450 2C9 (CYP2C9)

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CYP2C10; P450IIC9; Cytochrome P450,Subfamily IIC(Mephenytoin 4-Hydroxylase)Polypeptide 9; S-mephenytoin 4-hydroxylase

Cytochrome P450 2C9 (CYP2C9)
CCC Q090
HGNC 2623
PubMed 23863877
UniProt P11712
Wiki CYP2C9

CYP2C9 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. The binding mode of warfarin suggests that CYP2C9 may undergo an allosteric mechanism during its function.

The newly discovered binding pocket also suggests that CYP2C9 may simultaneously accommodate multiple ligands during its biologic function, and provides a possible molecular basis for understanding complex drug-drug interactions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome P450 2C9 (CYP2C9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome P450 2C9 (CYP2C9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome P450 2C9 (CYP2C9) Polyclonal Antibody Customized Service Offer
Assay Kits SEQ090Hu ELISA Kit for Cytochrome P450 2C9 (CYP2C9) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPQ090Ra01 Recombinant Cytochrome P450 2C9 (CYP2C9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAQ090Ra21 Monoclonal Antibody to Cytochrome P450 2C9 (CYP2C9) WB; IHC; ICC; IP.
PAQ090Ra01 Polyclonal Antibody to Cytochrome P450 2C9 (CYP2C9) WB; IHC; ICC; IP.
Assay Kits SEQ090Ra ELISA Kit for Cytochrome P450 2C9 (CYP2C9) Enzyme-linked immunosorbent assay for Antigen Detection.
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