The casein kinase I (CKI) gene family encodes serine/threonine kinases that preferentially phosphorylate acidic substrates using ATP as a phosphate donor. CKI proteins are monomeric and range from 25 to 55 kD. They are ubiquitous, being found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
The deduced 447-amino acid CSNK1G3 protein shares 98% sequence identity with rat CKI gamma-3. The authors also isolated a cDNA whose sequence is identical to that of the aforementioned CSNK1G3 cDNA except that it contains a 24-bp insertion in the coding sequence and an 8-bp insertion in the 3-prime untranslated region. They suggested that this cDNA represents an alternatively spliced CSNK1G3 transcript, which they named CSNK1G3L.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Casein Kinase 1 Gamma 3 (CSNK1g3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Casein Kinase 1 Gamma 3 (CSNK1g3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Casein Kinase 1 Gamma 3 (CSNK1g3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Casein Kinase 1 Gamma 3 (CSNK1g3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Casein Kinase 1 Gamma 3 (CSNK1g3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Casein Kinase 1 Gamma 3 (CSNK1g3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Casein Kinase 1 Gamma 3 (CSNK1g3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Casein Kinase 1 Gamma 3 (CSNK1g3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Casein Kinase 1 Gamma 3 (CSNK1g3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Casein Kinase 1 Gamma 3 (CSNK1g3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Casein Kinase 1 Gamma 3 (CSNK1g3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Casein Kinase 1 Gamma 3 (CSNK1g3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Casein Kinase 1 Gamma 3 (CSNK1g3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Casein Kinase 1 Gamma 3 (CSNK1g3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Casein Kinase 1 Gamma 3 (CSNK1g3) | ELISA Kit Customized Service Offer |
- "Cloning and chromosome mapping of the human casein kinase I gamma3 gene (CSNK1G3)."Cytogenet. Cell Genet. 83:101-103(1998) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
- "Structure of casein kinase 1 gamma 3."Submitted (MAR-2006) to the PDB data bank
- "Inhibitor binding by casein kinases."Submitted (FEB-2009) to the PDB data bank