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Oligomycin Sensitivity Conferring Protein (OSCP)

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ATP5O; ATPO; ATP Synthase,H+ Transporting,Mitochondrial F1 Complex O Subunit; ATP synthase subunit O, mitochondrial

Oligomycin Sensitivity Conferring Protein (OSCP)
CCC Q184
HGNC 850
MGI 106341
PubMed 15254386
RGD 621379
UniProt P48047
One of these nuclear genes (ATP5O) encodes the oligomycin sensitivity-conferring protein (OSCP) of ATP synthase and has been described from yeast, cow, and mouse. OSCP is a component of the 'stalk' region connecting the F1 and F0 domains of the ATP synthase complex.
The authors used exon trapping from pools of chromosome 21-specific cosmids to identify a portion of the gene, which was then used to screen a fetal brain cDNA library. The predicted polypeptide is 213 amino acids long with more than 80% identity to the bovine and mouse homologs. Northern blots showed that the gene was expressed in all human tissues examined and at highest levels in muscle and heart.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oligomycin Sensitivity Conferring Protein (OSCP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oligomycin Sensitivity Conferring Protein (OSCP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oligomycin Sensitivity Conferring Protein (OSCP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Oligomycin Sensitivity Conferring Protein (OSCP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oligomycin Sensitivity Conferring Protein (OSCP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oligomycin Sensitivity Conferring Protein (OSCP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oligomycin Sensitivity Conferring Protein (OSCP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oligomycin Sensitivity Conferring Protein (OSCP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Oligomycin Sensitivity Conferring Protein (OSCP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oligomycin Sensitivity Conferring Protein (OSCP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Oligomycin Sensitivity Conferring Protein (OSCP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Oligomycin Sensitivity Conferring Protein (OSCP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Oligomycin Sensitivity Conferring Protein (OSCP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Oligomycin Sensitivity Conferring Protein (OSCP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Oligomycin Sensitivity Conferring Protein (OSCP) ELISA Kit Customized Service Offer
  1. "Cloning of the cDNA for the human ATP synthase OSCP subunit (ATP5O) by exon trapping and mapping to chromosome 21q22.1-q22.2."Genomics 28:470-476(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
  5. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient and exercise-induced stress."Antioxid. Redox Signal. 0:0-0(2013)
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]