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Amylase Alpha 2B, Pancreatic (AMY2B)

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AMY2; 1,4-alpha-D-glucan glucanohydrolase 2B; Carcinoid alpha-amylase

Amylase Alpha 2B, Pancreatic (AMY2B)
CCC Q196
HGNC 478
PubMed 8268204
UniProt P19961
Wiki AMY2B
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. AMY2B encodes an amylase isoenzyme produced by the pancreas.
Large-scale copy number variations (LCVs) involve gains or losses of several kilobases to hundreds of kilobases of genomic DNA among phenotypically normal individuals. To investigate LCVs in the human genome, Iafrate et al. (2004) applied array-based comparative genomic hybridization (array CGH) to the genomes of 55 unrelated individuals.

Organism species: Homo sapiens (Human)

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n/a Polyclonal Antibody to Amylase Alpha 2B, Pancreatic (AMY2B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Amylase Alpha 2B, Pancreatic (AMY2B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Amylase Alpha 2B, Pancreatic (AMY2B) ELISA Kit Customized Service Offer
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  7. "Human pancreatic amylase is encoded by two different genes."Nucleic Acids Res. 16:4724-4724(1988) [PubMed] [Europe PMC] [Abstract]
  8. "Identification of the characteristic amino-acid sequence for human alpha-amylase encoded by the AMY2B gene."Biochim. Biophys. Acta 1203:224-229(1993) [PubMed] [Europe PMC] [Abstract]