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FAPP1 Associated Protein 1 (FASP1)

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C21orf45; B28; hMis18alpha; Phosphatidylinositol-Four-Phosphate Adaptor Protein1 Associated Protein-1

FAPP1 Associated Protein 1 (FASP1)
CCC Q226
HGNC 1286
MGI 1913828
PubMed 17199038
RGD 1310778
UniProt Q9NYP9
Wiki C21orf45
FASP1, was obtained by using yeast two-hybrid system. The interaction between pp5644 and FASP1 was experimentally confirmed by GST pull-down assay In vitro and co-immunoprecipitation assay in vivo. Co-localization of pp5644 and FASP1 in cytoplasm in Hela cells could further support the interaction. Based on the experimental results, it is suggested that pp5644 physically bind to FASP1 and the biological significance of this kind of interaction in vivo is discussed.
Tricostatin A, an inhibitor to histone deacetylase, suppresses the loss of CENP-A recruitment to centromeres in hMis18alpha RNAi cells. Telophase centromere chromatin may be primed or licensed by the hMis18 complex and RbAp46/48 to recruit CENP-A through regulating the acetylation status in the centromere.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant FAPP1 Associated Protein 1 (FASP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to FAPP1 Associated Protein 1 (FASP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to FAPP1 Associated Protein 1 (FASP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for FAPP1 Associated Protein 1 (FASP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for FAPP1 Associated Protein 1 (FASP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant FAPP1 Associated Protein 1 (FASP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to FAPP1 Associated Protein 1 (FASP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to FAPP1 Associated Protein 1 (FASP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for FAPP1 Associated Protein 1 (FASP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for FAPP1 Associated Protein 1 (FASP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant FAPP1 Associated Protein 1 (FASP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to FAPP1 Associated Protein 1 (FASP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to FAPP1 Associated Protein 1 (FASP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for FAPP1 Associated Protein 1 (FASP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for FAPP1 Associated Protein 1 (FASP1) ELISA Kit Customized Service Offer
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  5. "Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1."Dev. Cell 12:17-30(2007) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]