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Transmembrane Protein 50B (TMEM50B)

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C21orf4; HCV p7-trans-regulated protein 3

Transmembrane Protein 50B (TMEM50B)
CCC Q239
HGNC 1280
MGI 1925225
PubMed 18541381
RGD 1307561
UniProt P56557
Tmem50b, previously referred to as C21orf4, encodes a predicted transmembrane protein and is one of few genes significantly over-expressed during cerebellar development in a Down syndrome mouse model, Ts1Cje. In order to assess potential mechanisms by which Tmem50b could contribute to Down syndrome-related phenotypes, determined the expression patterns of Tmem50b mRNA, as well as Tmem50b protein distribution, expression and subcellular localization. In situ hybridization in mice at embryonic day 14.5 showed cortical plate and spinal cord mRNA expression. By postnatal day 7, strong mRNA expression was seen in the cerebellum, hippocampus and olfactory bulb, with diffuse cortical expression. Quantitative PCR of adult mouse tissue showed Tmem50b mRNA expression in the brain, heart and testis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 50B (TMEM50B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 50B (TMEM50B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 50B (TMEM50B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 50B (TMEM50B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 50B (TMEM50B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 50B (TMEM50B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 50B (TMEM50B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 50B (TMEM50B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 50B (TMEM50B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 50B (TMEM50B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane Protein 50B (TMEM50B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane Protein 50B (TMEM50B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane Protein 50B (TMEM50B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane Protein 50B (TMEM50B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane Protein 50B (TMEM50B) ELISA Kit Customized Service Offer
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