LRRFIP1 and LRRFIP2, encoding proteins that interact with the LRR domain of human FLI using the yeast two-hybrid system. LRRFIP1 exhibits sequence identity with the TRIP RNA-binding protein and GCF-2 transcriptional repressor, which are also related to the murine FLAP-1 gene. LRRFIP2 is a novel gene that shares sequence homology with LRRFIP1 and FLAP-1. LRRFIP1 and LRRFIP2 both express alternative splice variants in heart and skeletal muscle tissue. A coiled-coil domain, conserved within each encoded protein, serves as a potential interaction motif for FLI LRR. The occurrence of multiple proteins able to interact with FLI within the same tissue suggests that they may compete for the same binding site. Sequencing and PCR-directed genomic analysis indicate that LRRFIP1 and LRRFIP2 are related genes that arose from gene duplication.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Leucine Rich Repeat In FLII Interacting Protein 2 (LRRFIP2) | ELISA Kit Customized Service Offer |
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