Melanoma Antigen Family A9 (MAGEA9)

[Edit]

MAGE9; CT1.9; MAGE-9 Antigen; Melanoma-Associated Antigen 9; Cancer/Testis Antigen Family 1, Member 9

Melanoma Antigen Family A9 (MAGEA9)
MAGEA9B is a duplication of the MAGEA9 gene on chromosome Xq28. The 2 copies are separated by about 194 kb. Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
The MAGEA family consists of 12 genes (MAGEA1 to MAGEA12), of which 6, MAGEA1, MAGEA2, MAGEA3, MAGEA4, MAGEA6, and MAGEA12, are expressed in melanomas and other cancers. For further background information on the MAGEA family.De Plaen et al. (1994) identified the 12 MAGEA genes. MAGEA9 appeared to be a weakly expressed member of the family. Rogner et al. (1995) isolated a MAGEA9 cDNA from a fetal brain cDNA library.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Antigen Family A9 (MAGEA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Antigen Family A9 (MAGEA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Antigen Family A9 (MAGEA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Antigen Family A9 (MAGEA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Antigen Family A9 (MAGEA9) ELISA Kit Customized Service Offer
  1. "Structure, chromosomal localization, and expression of 12 genes of the MAGE family."Immunogenetics 40:360-369(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular and phenotypic variation in patients with severe Hunter syndrome."Hum. Mol. Genet. 6:479-486(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Terminal osseous dysplasia is caused by a single recurrent mutation in the FLNA gene."Am. J. Hum. Genet. 87:146-153(2010) [PubMed] [Europe PMC] [Abstract]