PMP22 is a major component of peroxisomal membranes in mammals.It seems to be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane. PMP22 is synthesized on free cytosolic ribosomes and then directed to the peroxisome membrane by specific targeting information. Previous studies in rats revealed that PMP22 contains one distinct peroxisomal membrane targeting signal in the amino-terminal cytoplasmic tail. Amino acid sequence alignment of rat and human protein revealed 77% identity including a high conservation of several protein motifs.Human as well as rat PMP22 contains two distinct and nonoverlapping peroxisomal membrane targeting signals, one in the amino-terminal and the other in the carboxyl-terminal protein region.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Peroxisomal Membrane Protein 2 (PXMP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Peroxisomal Membrane Protein 2 (PXMP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Peroxisomal Membrane Protein 2 (PXMP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Peroxisomal Membrane Protein 2 (PXMP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Peroxisomal Membrane Protein 2 (PXMP2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Peroxisomal Membrane Protein 2 (PXMP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Peroxisomal Membrane Protein 2 (PXMP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Peroxisomal Membrane Protein 2 (PXMP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Peroxisomal Membrane Protein 2 (PXMP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Peroxisomal Membrane Protein 2 (PXMP2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Peroxisomal Membrane Protein 2 (PXMP2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Peroxisomal Membrane Protein 2 (PXMP2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Peroxisomal Membrane Protein 2 (PXMP2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Peroxisomal Membrane Protein 2 (PXMP2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Peroxisomal Membrane Protein 2 (PXMP2) | ELISA Kit Customized Service Offer |
- "Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes."J. Biol. Chem. 277:774-784(2002) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis."J. Cell Biol. 148:931-944(2000) [PubMed] [Europe PMC] [Abstract]
- "The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22."Mol. Cell. Biochem. 287:147-155(2006) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]