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Serologically Defined Colon Cancer Antigen 1 (SDCCAG1)

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NEMF; NY-CO-1; Nuclear export mediator factor NEMF

Serologically Defined Colon Cancer Antigen 1 (SDCCAG1)
CCC Q331
HGNC 10663
MGI 1918305
PubMed 16103875
UniProt O60524
By SEREX (serologic analysis of recombinant cDNA expression libraries), Scanlan et al. (1998) cloned SDCCAG1, which they called NY-CO-1, from a colon cancer cDNA library. The deduced 362-amino acid protein contains a nuclear targeting signal.
The screening of cDNA expression libraries derived from human tumors with autologous antibody (SEREX) has proven to be a powerful method for defining the structure of tumor antigens recognized by the humoral immune system. In the present study, 48 distinct antigens (NY-CO-1-NY-CO-48) reactive with autologous IgG were identified by SEREX analysis in 4 patients with colon cancer. Sequencing analysis showed that 17 of the cDNA clones were previously uncharacterized molecules and 31 represented known gene products.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serologically Defined Colon Cancer Antigen 1 (SDCCAG1) ELISA Kit Customized Service Offer
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