Cadherin 24 (CDH24)
Cadherin-24 is a type II cadherin with a 781-codon open reading frame, which encodes a type II cadherin protein complete with five extracellular repeats containing calcium-binding motifs, a transmembrane domain, and a conserved cytoplasmic domain. Cadherin-24 has the unusual feature of being alternatively spliced in extracellular repeat 4. This alternative exon encodes 38 in-frame amino acids, resulting in an 819-amino-acid protein. Sequence analysis suggests the presence of beta-catenin and p120 catenin-binding sequences, and immunoprecipitation experiments confirm the ability of both forms of the novel cadherin to associate with alpha-catenin, beta-catenin, and p120 catenin. In addition, aggregation assays show that both forms of cadherin-24 mediate strong cell-cell adhesion.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cadherin 24 (CDH24) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cadherin 24 (CDH24) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cadherin 24 (CDH24) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cadherin 24 (CDH24) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cadherin 24 (CDH24) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cadherin 24 (CDH24) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cadherin 24 (CDH24) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cadherin 24 (CDH24) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cadherin 24 (CDH24) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cadherin 24 (CDH24) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cadherin 24 (CDH24) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cadherin 24 (CDH24) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cadherin 24 (CDH24) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cadherin 24 (CDH24) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cadherin 24 (CDH24) ELISA Kit Customized Service Offer
  1. "Characterization of cadherin-24, a novel alternatively spliced type II cadherin."J. Biol. Chem. 278:27513-27519(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]