Cadherin-24 is a type II cadherin with a 781-codon open reading frame, which encodes a type II cadherin protein complete with five extracellular repeats containing calcium-binding motifs, a transmembrane domain, and a conserved cytoplasmic domain. Cadherin-24 has the unusual feature of being alternatively spliced in extracellular repeat 4. This alternative exon encodes 38 in-frame amino acids, resulting in an 819-amino-acid protein. Sequence analysis suggests the presence of beta-catenin and p120 catenin-binding sequences, and immunoprecipitation experiments confirm the ability of both forms of the novel cadherin to associate with alpha-catenin, beta-catenin, and p120 catenin. In addition, aggregation assays show that both forms of cadherin-24 mediate strong cell-cell adhesion.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cadherin 24 (CDH24) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cadherin 24 (CDH24) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cadherin 24 (CDH24) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cadherin 24 (CDH24) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cadherin 24 (CDH24) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cadherin 24 (CDH24) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cadherin 24 (CDH24) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cadherin 24 (CDH24) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cadherin 24 (CDH24) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cadherin 24 (CDH24) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cadherin 24 (CDH24) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cadherin 24 (CDH24) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cadherin 24 (CDH24) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cadherin 24 (CDH24) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cadherin 24 (CDH24) | ELISA Kit Customized Service Offer |
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